VEXAS syndrome
The American College of Rheumatology guidance statement on VEXAS syndrome
Published in March 2026, it sets out what an international panel considers established about the diagnosis, treatment and monitoring of a disease first described in 2020, and what is not.
At a glance
| Position | Professor of internal medicine and clinical immunology, hospital practitioner (PU-PH) |
|---|---|
| Where | Sorbonne Université and Saint-Antoine Hospital (AP-HP), Paris; Saint-Antoine Research Centre, Inserm UMR_S 938 |
| Areas | VEXAS syndrome, autoinflammatory diseases and inflammatory amyloidosis, systemic autoimmune diseases, reproductive immunology, inflammatory manifestations of myeloid malignancies |
| Cited work | First author of the American College of Rheumatology guidance statement on VEXAS syndrome (Arthritis & Rheumatology, March 2026, DOI 10.1002/art.43287) |
| Networks | Co-founder and coordinator of FRENVEX, the French VEXAS study group (2020); founder and chair of the MINHEMON network (2016); head of the CeRéMAIA constitutive site at Saint-Antoine Hospital, acquired inflammatory disorders including VEXAS syndrome |
| Teaching | Director of the university diploma in reproductive immunology, Sorbonne Université (since 2024) |
| Commitment | Founder and chair of the Santé Arménie association (2020) |
| Identifiers | ORCID 0000-0003-2849-3049 · Scopus 23973320800 · IdRef 131898493 |
Research areas
VEXAS syndrome
Acquired adult-onset autoinflammatory disease caused by somatic UBA1 mutation.
Reproductive immunology
Immune tolerance in pregnancy and repeated pregnancy failure.
Recurrent early pregnancy loss
When the standard work-up is negative: the internal medicine approach.
Antiphospholipid syndrome
Obstetric and refractory forms; the place of hydroxychloroquine.
Recurrent implantation failure
Immune investigations after repeated embryo transfers.
Inflammatory placental disease
Chronic histiocytic intervillositis, chronic villitis, massive perivillous fibrin deposition.
Pregnancy and autoimmune diseases
Preconception planning and treatment adjustment.
Autoinflammatory diseases and AA amyloidosis
Familial Mediterranean fever and related syndromes; CeRéMAIA reference centre.
News
The first long-form pages will appear here.
Each will deal with one precise subject, with its sources and with what is not yet known.
Each will deal with one precise subject, with its sources and with what is not yet known.